Phenylbutazone Paste is a synthetic, non-hormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties. Chemically, Phenylbutazone Paste is 4-butyl-1, 2-diphenyl-3, 5-pyrazolidinedione.. Horses (450kg bodyweight) 4.4mg/kg bodyweight as 10mL oral paste (equivalent to phenylbutazone 2g) twice on first day, followed by 2.2mg/kg as 5mL (phenylbutazone 1g) twice daily for four days, followed by 5mL (phenylbutazone 1g) daily or every second day as required. Ponies (225kg bodyweight) 5mL (phenylbutazone 1g) daily for four days.

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However, care should be taken as it may also mask other symptoms of an ill horse. Recomended dosage of bute: Day 1 - (8.8mg/kg per day) Days 2 -5 (4.4mg/kg per day): Side effects of phenylbutazone. Bute works well for horses for short-term pain relief. But it can be toxic if used in too high of a dose.. Calculate the dosage: Once you have the horse's weight, calculate the dosage of Bute based on the recommended range of 1-2 mg per pound of body weight. For example, if the horse weighs 1000 pounds, the dosage will be between 1000-2000 mg of Bute. Determine the frequency: Consult with a veterinarian to determine the frequency of Bute administration.